This unit of study focuses on pathophysiological concepts and processes related to human responses to disease and illness. Using a conceptual approach, students will be provided with the opportunity to apply research findings to gain a deeper understanding of patient assessment information. The conceptual approach assists students to focus on clinical problems encountered across common disease categories and populations. This approach assists nurses in developing a systematic approach when making observations and formulating questions for further investigations about events or conditions that influence patient signs and symptoms. The application of these processes and concepts provides a knowledge base for registered nurses to improve clinical judgements and decision-making in the management of patients with complex changes in health status. Students will undertake a further period of supernumerary integrated professional practice (SIPP) (60 hours) verified by their approved supervisor concurrently while undertaking this unit of study.